Aminobenzenesulfonic auristatin E

Names

[ Name ]:
Aminobenzenesulfonic auristatin E

Biological Activity

[Description]:

Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC with potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[Target]

Auristatin

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₆₄N₆O₈S

[ Molecular Weight ]:
753.00

Aminobenzenesulfonic auristatin E

Names

Biological Activity

Chemical & Physical Properties

Related Compounds