N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite

Names

[ CAS No. ]:
179479-02-8

[ Name ]:
N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite

[Synonym ]:
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3'-O-methyl-
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-3'-O-methyladenosine

Biological Activity

[Description]:

N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine 3'CE-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Molecular Formula ]:
C48H54N7O8P

[ Molecular Weight ]:
887.96

[ Exact Mass ]:
887.377136

[ LogP ]:
10.55

Related Compounds

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