VUF11207 fumarate

Names

[ Name ]:
VUF11207 fumarate

Biological Activity

[Description]:

VUF11207 fumarate (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7[1].

[Related Catalog]:

Research Areas >> Endocrinology

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> CXCR

Signaling Pathways >> Immunology/Inflammation >> CXCR

[Target]

CXCR7:8.1 (pKi)

[References]

[1]. Wijtmans M, et al. Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur J Med Chem. 2012 May;51:184-92.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₉FN₂O₈

[ Molecular Weight ]:
586.65

[ Storage condition ]:
-20°C

Related Compounds

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