1785665-61-3

1785665-61-3 structure

Name: VUF11207 fumarate
Chemical Name: VUF 11207 fumarate
CAS Number: 1785665-61-3
Molecular Formula: C₃₁H₃₉FN₂O₈
Molecular Weight: 586.65
Catalog: Signaling Pathways GPCR/G Protein CXCR
Create Date: 2018-07-13 23:28:37
Modify Date: 2025-09-17 19:53:02
VUF11207 fumarate (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7[1].

Name	VUF 11207 fumarate

Description	VUF11207 fumarate (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7[1].
Related Catalog	Research Areas >> Endocrinology Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR7:8.1 (pKi)
References	[1]. Wijtmans M, et al. Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur J Med Chem. 2012 May;51:184-92.