Zapalog

Names

[ Name ]:
Zapalog

Biological Activity

[Description]:

Zapalog is a photocleavable small-molecule heterodimerizer that can be used to repeatedly initiate, and instantaneously terminate, a physical interaction between two target proteins. Zapalog dimerizes any two proteins tagged with the FKBP and DHFR domains until exposure to light causes its photolysis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Gutnick A, et al. The light-sensitive dimerizer zapalog reveals distinct modes of immobilization for axonal mitochondria. Nat Cell Biol. 2019 Jun;21(6):768-777.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₈H₇₃N₇O₁₅

[ Molecular Weight ]:
1108.24

Related Compounds

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