Fmoc-D-Allo-Thr(tBu)-OH

Names

[ Name ]:
Fmoc-D-Allo-Thr(tBu)-OH

[Synonym ]:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-D-allothreonine
D-Allothreonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-D-Allo-Thr(tBu)-OH

Biological Activity

[Description]:

FMOC-D-Allo-THR(TBU)-OH is a D-allothreonine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

FMOC-D-Allo-THR(TBU)-OH can be synthesized by Fischer and Sandosham through the protection of hydroxy groups with the tBu using H2SO4/2-methylpropene and deprotection of tBu ester by 25% Cl2CHCOOH in 8% yield[1].

[References]

[1]. Mari Kikuchi, et al. Improved synthesis of d-allothreonine derivatives from l-threonine. Tetrahedron. 26 August 2013, 69(34):7098-7101.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
581.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₃H₂₇NO₅

[ Molecular Weight ]:
397.464

[ Flash Point ]:
305.6±30.1 °C

[ Exact Mass ]:
397.188934

[ PSA ]:
84.86000

[ LogP ]:
5.45

[ Appearance of Characters ]:
Powder | White

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.569

[ Storage condition ]:
2-8°C

MSDS

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Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds

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