nAChR modulator-2

Names

[ CAS No. ]:
1700657-87-9

[ Name ]:
nAChR modulator-2

Biological Activity

[Description]:

nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

[In Vitro]

nAChR modulator-2 (compound 2) inhibits three major pests, the larvae of the banded cucumber beetle Diabrotica balteata, the green peach aphid M. persicae, and the cotton leafworm Spodoptera littoralis,with EC90 values of 200 mg/L, 3.12 mg/L, and 200 mg/L[1].

[References]

[1]. Mark Montgomery, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators. J Med Chem. 2022 Feb 10;65(3):2297-2312.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₈ClN₃O₂

[ Molecular Weight ]:
261.66

Related Compounds

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