(4-Chlorophenyl)boronic acid
Names
[ CAS No. ]:
1679-18-1
[ Name ]:
(4-Chlorophenyl)boronic acid
[Synonym ]:
4-Chlorophenylboranic acid
p-chlorophenylboronic aci
para-chlorophenylboronic acid
(4-Chlorophenyl)boronic acid
para-chlorobenzene boronic acid
4-CHLOROPHENYLBORNIC ACID
p-chloro-benzeneboronicaci
MFCD00039137
boronicacid,p-chlorophenyl
4-Chlorophenylboronic acid
EINECS 216-845-5
4-chlorobenzeneboronic acid
4-Chloro phenyl boronic acid
p-chlorophenylboronic acid
p-chlorobenzeneboronic acid
RARECHEM AH PB 0178
Boronic acid, B-(4-chlorophenyl)-
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
295.4±42.0 °C at 760 mmHg
[ Melting Point ]:
284-289 °C(lit.)
[ Molecular Formula ]:
C6H6BClO2
[ Molecular Weight ]:
156.375
[ Flash Point ]:
132.4±27.9 °C
[ Exact Mass ]:
156.014938
[ PSA ]:
40.46000
[ LogP ]:
2.18
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.558
[ Storage condition ]:
Refrigerator (+4°C)
[ Water Solubility ]:
2.5 g/100 mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY8950000
- CHEMICAL NAME :
- Benzeneboronic acid, p-chloro-
- CAS REGISTRY NUMBER :
- 1679-18-1
- BEILSTEIN REFERENCE NO. :
- 2936346
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H6-B-Cl-O2
- MOLECULAR WEIGHT :
- 156.38
- WISWESSER LINE NOTATION :
- QBQR DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00061
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S36-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CY8950000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Org. Lett. 7th ed., 14 , 1756-1759, (2012)
Cationic Pd(II)-catalyzed enantioselective arylative cyclization of alkyne-tethered enals or enones initiated by carbopalladation of alkynes was developed without the necessity of a redox system.
Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates.Org. Lett. 7th ed., 14 , 1930-1933, (2012)
A Ru-catalyzed direct arylation of benzylic sp(3) carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combin...
Tandem-type Pd(II)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: a novel route to 4-aryl-2-quinolinones.Chem. Commun. (Camb.) 36th ed., 48 , 4332-4334, (2012)
A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential Pd(II)-catalyzed reactions--the oxidative Heck reaction an...