N-Cbz-L-serine methyl ester

Names

[ Name ]:
N-Cbz-L-serine methyl ester

[Synonym ]:
L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester
Methyl N-[(benzyloxy)carbonyl]-L-serinate
N-Carbobenzyloxy-L-serine methyl ester
N-Carbobenzoxy-L-serine Methyl Ester
CBZ-L-Serine methyl ester
N-Cbz-L-serine Methyl Ester
N-Benzyloxycarbonyl-l-serine, methyl ester
MFCD00077039
Cbz-Ser-OMe
(S)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate
methyl (2S)-3-hydroxy-2-(phenylmethoxycarbonylamino)propanoate
Z-Ser-OMe

Biological Activity

[Description]:

Z-Ser-OMe is a serine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
442.6±45.0 °C at 760 mmHg

[ Melting Point ]:
41-43 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₅NO₅

[ Molecular Weight ]:
253.251

[ Flash Point ]:
221.5±28.7 °C

[ Exact Mass ]:
253.095016

[ PSA ]:
84.86000

[ LogP ]:
1.42

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.536

[ Storage condition ]:
-15°C

MSDS

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Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Stereoselective Synthesis of Differentially Protected Derivatives of the Higher Amino Sugars Destomic Acid and Lincosamine from Serine and Threonine.

J. Org. Chem. 61 , 581, (1996)

The aminoheptose destomic acid (3.5) and the aminooctose lincosamine (6.8) were synthesized in protected form by parallel sequences starting from the oxazolidine derivatives 2.4 and 5.1 of N-CBz serin...

Monache, G.D. et al.

Synthesis , 1155, (1995)

Demirci, F. et al.

Synthesis , 189, (1996)