Diphenyl phosphate

Names

[ CAS No. ]:
838-85-7

[ Name ]:
Diphenyl phosphate

[Synonym ]:
Phenol hydrogen phosphate
diphenylphosphoric acid
EINECS 212-657-2
Diphenyl hydrogen phosphate
diphenylhydrogenphosphate
MFCD00003033
Diphenyl phosphate
(PhO)2P(O)OH
Phosphoric acid, diphenyl ester
Biphenyl Ester
diphenyl phosphoric acid
Phosphoric acid diphenyl
PHOSPHORIC ACID DIPHENYL ESTER
phenylphosphate((pho)2(ho)po)

Biological Activity

[Description]:

Diphenyl Phosphate inhibits growth and energy metabolism of zebrafish in a sex-specific manner.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55(19):13122-13131.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
377.7±25.0 °C at 760 mmHg

[ Melting Point ]:
62-66 °C(lit.)

[ Molecular Formula ]:
C₁₂H₁₁O₄P

[ Molecular Weight ]:
250.19

[ Flash Point ]:
182.3±23.2 °C

[ Exact Mass ]:
250.039490

[ PSA ]:
65.57000

[ LogP ]:
1.34

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.588

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TC5470000

CHEMICAL NAME :: Phosphoric acid, diphenyl ester

CAS REGISTRY NUMBER :: 838-85-7

BEILSTEIN REFERENCE NO. :: 1379164

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H11-O4-P

MOLECULAR WEIGHT :: 250.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Phage inhibition capacity

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 25 ug/well

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 260,349,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1941 No. of Facilities: 105 (estimated) No. of Industries: 5 No. of Occupations: 5 No. of Employees: 1473 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1941 No. of Facilities: 123 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1608 (estimated) No. of Female Employees: 708 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TC5470000

[ HS Code ]:
29190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2919900090

[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

Evaluation of two passive samplers for the analysis of organophosphate esters in the ambient air.

Talanta 147 , 69-75, (2015)

Both polyurethane foam (PUF) and sorbent-impregnated PUF (SIP) passive air sampling (PAS) methods were deployed and compared separately for the analysis of organophosphate esters (OPEs) in outdoor atm...

In vitro drug release and biological evaluation of biomimetic polymeric micelles self-assembled from amphiphilic deoxycholic acid-phosphorylcholine-chitosan conjugate.

Mater. Sci. Eng. C. Mater. Biol. Appl. 45 , 162-9, (2014)

Novel biomimetic amphiphilic chitosan derivative, deoxycholic acid-phosphorylcholine-chitosan conjugate (DCA-PCCs) was synthesized based on the combination of Atherton-Todd reaction for coupling phosp...

Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.

J. Biol. Chem. 286(10) , 7822-9, (2011)

The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a me...