3-Amino-4-cyanopyrazole

Names

[ Name ]:
3-Amino-4-cyanopyrazole

[Synonym ]:
3-Amino-1H-pyrazole-4-carbonitrile
pyrazolecarbonitrile
3-Aminopyrazole-4-Carbonitrile
3-Amino-4-cyanopyrrole
Zaleplon intermediate
5-amino-4-pyrazolecarbonitrile
3-Amino-4-cyanopyrazole
5-aminopyrazole-4-carbonitrile
5-AMINO-4-CYANOPYRAZOLE
EINECS 240-665-6
3-aminopyrazolo-4-carbonitrile
1H-Pyrazole-4-carbonitrile, 3-amino-
3-Amino-4-pyrazolecarbonitrile
5-amino-1H-pyrazole-4-carbonitrile
MFCD00005237
3-amino-4-cyano-1H-pyrazole
4-cyano-5-aminopyrazole
Allopurinol Impurity 7

Biological Activity

[Description]:

3-Amino-4-pyrazolecarbonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
476.4±30.0 °C at 760 mmHg

[ Melting Point ]:
172-174 °C(lit.)

[ Molecular Formula ]:
C₄H₄N₄

[ Molecular Weight ]:
108.10

[ Flash Point ]:
241.9±24.6 °C

[ Exact Mass ]:
108.043594

[ PSA ]:
78.49000

[ LogP ]:
0.66

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21

[ Safety Phrases ]:
S22-S24/25-S23

[ RIDADR ]:
3439

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29331990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo.

Mol. Cell. Endocrinol. 393(1-2) , 56-64, (2014)

CLM29 (a pyrazolo[3,4-d]pyrimidine, that inhibits RET, epidermal growth factor receptor, vascular endothelial growth factor receptor, and has an anti-angiogenic activity) has anti-neoplastic activity ...

Synlett , 65, (2006)

Helv. Chim. Acta 89 , 30, (2006)