Fremanezumab

Names

[ Name ]:
Fremanezumab

Biological Activity

[Description]:

Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CGRP Receptor

Signaling Pathways >> Neuronal Signaling >> CGRP Receptor

Research Areas >> Neurological Disease

[References]

[1]. Stephen D Silberstein, et al. Fremanezumab for the Preventive Treatment of Chronic Migraine. N Engl J Med. 2017 Nov 30;377(22):2113-2122.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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