MC-100093
Names
[ CAS No. ]:
1639784-02-3
[ Name ]:
MC-100093
Biological Activity
[Description]:
MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.
[References]
1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59.
Chemical & Physical Properties
[ Molecular Formula ]:
C13H23N3O3
[ Molecular Weight ]:
269.345
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.