1639784-02-3
1639784-02-3 structure
- Name: MC-100093
- Chemical Name: MC-100093
- CAS Number: 1639784-02-3
- Molecular Formula: C13H23N3O3
- Molecular Weight: 269.345
- Create Date: 2022-07-04 11:07:03
- Modify Date: 2023-01-16 10:41:51
-
MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.
| Name | MC-100093 |
|---|
| Description | MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.MC-100093 restored the expression of NA core GLT-1.MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight. |
|---|---|
| References | 1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59. |
| Molecular Formula | C13H23N3O3 |
|---|---|
| Molecular Weight | 269.345 |