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LY3177833

Names

[ CAS No. ]:
1627696-51-8

[ Name ]:
LY3177833

[Synonym ]:
(3R)-3-(5-fluoropyrimidin-4-yl)-3-methyl-6-(1H-pyrazol-4-yl)-2H-isoindol-1-one

Biological Activity

[Description]:

LY3177833 is an CDC7 and pMCM2 inhibitor extracted from patent US 20140275131and patent WO 2014143601 A1 compound example 4; has IC50 values of 3.3 nM and 290 nM, respectively.

[Related Catalog]:

Research Areas >> Cancer

[Target]

Cdc7:3.3 nM (IC50)

pMCM2:290 nM (IC50)


[References]

[1]. WO2014143601A1


[Related Small Molecules]

Abemaciclib(LY2835219) | Ribociclib (LEE011) | Dinaciclib (SCH727965) | THZ1 2HCl | Roscovitine (CYC202) | THZ531 | RO-3306 | Flavopiridol | NVP 2 | BAY-1143572 Racemate | CYC-065 | AZD5438 | BIO | Kenpaullone | SNS-032 (BMS-387032)

Chemical & Physical Properties

[ Molecular Formula ]:
C16H12FN5O

[ Molecular Weight ]:
309.304

[ Exact Mass ]:
309.103

[ Storage condition ]:
2-8℃

Related Compounds

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