Pf-06371900

Names

[ CAS No. ]:
1622291-81-9

[ Name ]:
Pf-06371900

Biological Activity

[Description]:

PF-06371900 is a potent and highly selective leucine rich repeat kinase 2 (LRRK2) inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Autophagy >> LRRK2

Research Areas >> Neurological Disease

[References]

[1]. Henderson JL, et al. Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆N₆O₂S

[ Molecular Weight ]:
368.41

Related Compounds

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