ROCK-IN-8

Names

[ CAS No. ]:
1621103-79-4

[ Name ]:
ROCK-IN-8

Biological Activity

[Description]:

ROCK-IN-8 (Example 4) is a ROCK inhibitor, with an IC50 value less than 100 nM. ROCK-IN-8 has anti-inflammatory activity. ROCK-IN-8 can be used for research of respiratory and gastro-intestinal diseases[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Stem Cell/Wnt >> ROCK
Signaling Pathways >> TGF-beta/Smad >> ROCK

[References]

[1]. Sandro Boland, et al. Pyridine derivatives as soft rock inhibitors. Patent. WO2014118133.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H25FN4O4S

[ Molecular Weight ]:
556.61

Related Compounds

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