N1-(1,1,1-Trifluoroethyl)pseudouridine

Names

[ CAS No. ]:
1613529-80-8

[ Name ]:
N1-(1,1,1-Trifluoroethyl)pseudouridine

Biological Activity

[Description]:

N1-(1,1,1-Trifluoroethyl)pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H13F3N2O6

[ Molecular Weight ]:
326.23

Related Compounds

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