PF-06256142

Names

[ Name ]:
PF-06256142

Biological Activity

[Description]:

PF-06256142 is a potent and selective orthosteric agonist of the D1 receptor, with D1 EC50=30 nM and D1 binding Ki = 12 nM.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018 Nov 15.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₆N₄O₂

[ Molecular Weight ]:
356.38

Related Compounds

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