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(R)-PF-06256142

Names

[ CAS No. ]:
1609583-15-4

[ Name ]:
(R)-PF-06256142

Biological Activity

[Description]:

(R)-PF-06256142 is the R enantiomer of PF-06256142 with low active. PF-06256142 is a potent and selective orthosteric D1 receptor agonist that can reduce receptor desensitization relative to dopamine and other catechol-containing agonists[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018;61(24):11384-11397.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H16N4O2

[ Molecular Weight ]:
356.38

Related Compounds