BAY-747
Names
[ CAS No. ]:
1609341-78-7
[ Name ]:
BAY-747
Biological Activity
[Description]:
BAY-747 (BAY747) is a novel potent, selective, brain-penetrant soluble guanylate cyclase (sGC) stimulator.Oral administration of BAY-747 to male Wistar rats enhanced memory acquisition in the object location task (OLT), reversed L-NAME induced memory impairments in the OLT.BAY-747 enhanced hippocampal GluA1-containing AMPA receptor (AMPAR) trafficking in a chemical LTP model for memory acquisition using acute mouse hippocampal slices in ex vivo.
[References]
1. Nelissen E, et al. Sci Rep. 2022 Mar 4;12(1):3589.
Chemical & Physical Properties
[ Molecular Formula ]:
C22H26F2N4O2
[ Molecular Weight ]:
416.473
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.