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MPDC

Names

[ CAS No. ]:
159262-32-5

[ Name ]:
MPDC

[Synonym ]:
3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid, (1R,2S,5S,6S)-
(1R,2S,5S,6S)-3-Azabicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Biological Activity

[Description]:

MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GlyT
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> GlyT

[Target]

Glutamate transporter[1].


[References]

[1]. Bridges RJ, et al. A conformationally constrained competitive inhibitor of the sodium-dependent glutamate transporter in forebrain synaptosomes: L-anti-endo-3,4-methanopyrrolidine dicarboxylate. Neurosci Lett. 1994 Jun 20;174(2):193-7.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
381.2±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H9NO4

[ Molecular Weight ]:
171.15

[ Flash Point ]:
184.4±27.9 °C

[ Exact Mass ]:
171.053162

[ LogP ]:
-1.43

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.594

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds