Casein kinase 1δ-IN-5

Names

[ CAS No. ]:
1579991-10-8

[ Name ]:
Casein kinase 1δ-IN-5

Biological Activity

[Description]:

Casein kinase 1δ-IN-5 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 47 nM. Casein kinase 1δ-IN-5 shows neuroprotective and anti-inflammatory properties both in vitro. Casein kinase 1δ-IN-5 has the potential for neurodegenerative diseases research.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase
Research Areas >> Neurological Disease
Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[Target]

CK1δ:47 nM (IC50)


[References]

[1]. José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega  

Chemical & Physical Properties

[ Molecular Formula ]:
C16H11F3N2OS

[ Molecular Weight ]:
336.33

Related Compounds

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