Casein kinase 1δ-IN-6

Names

[ Name ]:
Casein kinase 1δ-IN-6

Biological Activity

[Description]:

Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase

Research Areas >> Neurological Disease

Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[References]

[1]. José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₀ClF₃N₂OS

[ Molecular Weight ]:
370.78

Related Compounds

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