Btk inhibitor 1 (R enantiomer hydrochloride)

Names

[ Name ]:
Btk inhibitor 1 (R enantiomer hydrochloride)

[Synonym ]:
Btk inhibitor 1 (R enantiomer hydrochloride)
3-(4-Phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride (1:1)

Biological Activity

[Description]:

Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.IC50 value:Target: BtkFrom PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

Research Areas >> Cancer

[References]

[1]. PCT Int. Appl. (2012), WO 2012158843 A2 20121122.

[Related Small Molecules]

Acalabrutinib | GDC-0853 | Evobrutinib | AVL-292 | (±)-Zanubrutinib | ONO-4059 | BMX-IN-1 | GDC-0834 | SNS-062 | RN486 | LFM-A13 | Vecabrutinib | CGI-1746 | BMS-986195 | CNX-774

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃ClN₆O

[ Molecular Weight ]:
422.91100

[ Exact Mass ]:
422.16200

[ PSA ]:
90.88000

[ LogP ]:
5.50430

[ Storage condition ]:
2-8℃

Related Compounds

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