4’-Methyladenosine

Names

[ CAS No. ]:
152540-76-6

[ Name ]:
4’-Methyladenosine

[Synonym ]:
C-4'-methyladenosine
9H-Purin-6-amine, 9-[5-deoxy-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-
9-[5-Deoxy-4-(hydroxymethyl)-α-L-lyxofuranosyl]-9H-purin-6-amine

Biological Activity

[Description]:

4’-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
643.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H15N5O4

[ Molecular Weight ]:
281.27

[ Flash Point ]:
342.9±34.3 °C

[ Exact Mass ]:
281.112396

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.823

Related Compounds

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