N-[(Benzyloxy)carbonyl]norleucine

Names

[ Name ]:
N-[(Benzyloxy)carbonyl]norleucine

[Synonym ]:
N-benzyloxycarbonyl-DL-norleucine
Cbz-D-norleucine
carbobenzoxyaminocaproic acid
Z-DL-norleucine
N-Carbobenzoxy-DL-norleucine
Z-D-Nle-OH
N-Benzyloxycarbonyl-D-norleucine
N-Cbz-(D,L)-norleucine
Cbz-DL-norleucine
N-[(Benzyloxy)carbonyl]norleucine
DL-Z-Nor-Leu-OH
Z-DL-Nle-OH
N-benzyloxycarbonylnorleucine
DL-CBZ-Norleucine
Z-D-norleucine
Norleucine, N-[(phenylmethoxy)carbonyl]-
D-Z-Nor-Leu-OH
MFCD00063169
N-Benzyloxycarbonyl-DL-norleucin
N-Cbz-DL-norleucine

Biological Activity

[Description]:

Cbz-D-norleucine (Z-D-NLE-OH) is a derivative of norleucine, can be used for preparing drugs or other compounds[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Brosowsky, et al. Syntheses of thailandepsin B pseudo-natural products: Access to new highly potent HDAC inhibitors via late-stage modification. Chemistry - A European Journal (2020), 26(69), 16241-16245

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
449.2±38.0 °C at 760 mmHg

[ Melting Point ]:
56-58ºC

[ Molecular Formula ]:
C₁₄H₁₉NO₄

[ Molecular Weight ]:
265.305

[ Flash Point ]:
225.5±26.8 °C

[ Exact Mass ]:
265.131409

[ PSA ]:
75.63000

[ LogP ]:
3.31

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.529

[ Storage condition ]:
Store at RT.

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%