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Sofosbuvir impurity K

Names

[ CAS No. ]:
1496552-51-2

[ Name ]:
Sofosbuvir impurity K

[Synonym ]:
Isopropyl (2S)-2-{[{[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-3-hydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
Uridine, 2'-chloro-2'-deoxy-2'-methyl-5'-O-[[[(1S)-1-methyl-2-(1-methylethoxy)-2-oxoethyl]amino]phenoxyphosphinyl]-
Sofosbuvir Impurity 28

Biological Activity

[Description]:

Sofosbuvir impurity K, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HCV
Research Areas >> Infection
Research Areas >> Others

[Target]

HCV[1]


[Related Small Molecules]

Asunaprevir | Sofosbuvir | Simeprevir | Ledipasvir | paritaprevir | Artemisinin | Elbasvir | NIM811 | MK-5172 | velpatasvir | Ombitasvir | Danoprevir (ITMN-191) | Glecaprevir | Celgosivir (hydrochloride) | Alisporivir

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C22H29ClN3O9P

[ Molecular Weight ]:
545.907

[ Exact Mass ]:
545.132996

[ LogP ]:
1.45

[ Index of Refraction ]:
1.588

[ Storage condition ]:
2-8℃

Related Compounds