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MG 1

Names

[ CAS No. ]:
148274-76-4

[ Name ]:
MG 1

[Synonym ]:
2-Pyrrolidinone,1-(2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl)
MG-1
1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl]pyrrolidin-2-one
1-(2-Hydroxy-3-(4-phenyl-1-piperazinyl)propyl)-2-pyrrolidinone
MG 1

Biological Activity

[Description]:

MG 1 is an α1 adrenergic receptor antagonist.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Research Areas >> Cardiovascular Disease

[Target]

Adrenergic receptor[1]


[In Vitro]

Refer to the compound 23[1].

[References]

[1]. Nowaczyk A, et al. QSAR studies on a number of pyrrolidin-2-one antiarrhythmic arylpiperazinyls. Med Chem Res. 2012 Mar;21(3):373-381.


[Related Small Molecules]

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | Adrenaline | Ivabradine hydrochloride | Prazosin hydrochloride | Clenbuterol hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | pimozide | Sotalol hydrochloride | Carvedilol | Atenolol | Metroprolol succinate

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
529.5ºC at 760mmHg

[ Molecular Formula ]:
C17H25N3O2

[ Molecular Weight ]:
303.39900

[ Flash Point ]:
274ºC

[ Exact Mass ]:
303.19500

[ PSA ]:
47.02000

[ LogP ]:
0.73270

[ Vapour Pressure ]:
4.86E-12mmHg at 25°C

[ Index of Refraction ]:
1.58

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Related Compounds