PF 04885614

Names

[ Name ]:
PF 04885614

[Synonym ]:
2-{4-[4-(Trifluoromethoxy)phenyl]-1H-imidazol-2-yl}-2-propanamine
1H-Imidazole-2-methanamine, α,α-dimethyl-4-[4-(trifluoromethoxy)phenyl]-
MFCD26792589

Biological Activity

[Description]:

PF-04885614 is a potent NaV1.8 inhibitor, extracted from patent US2018328915. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Neurological Disease

[References]

[1]. Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
414.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₄F₃N₃O

[ Molecular Weight ]:
285.265

[ Flash Point ]:
204.6±28.7 °C

[ Exact Mass ]:
285.108887

[ LogP ]:
3.13

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.527

Related Compounds

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