Methyl ethanimidate hydrochloride (1:1)

Names

[ Name ]:
Methyl ethanimidate hydrochloride (1:1)

[Synonym ]:
EINECS 238-843-3
methyl ethanimidate,hydrochloride
ACETIMIDIC ACID METHYL ESTER,HYDROCHLORIDE
MFCD00012571
Methyl ethanimidoate hydrochloride (1:1)
Ethanimidic acid, methyl ester, hydrochloride (1:1)
Methyl ethanimidate hydrochloride (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
24.4ºC at 760mmHg

[ Melting Point ]:
105ºC (dec.)(lit.)

[ Molecular Formula ]:
C₃H₈ClNO

[ Molecular Weight ]:
109.555

[ Flash Point ]:
5.7ºC

[ Exact Mass ]:
109.029442

[ PSA ]:
33.08000

[ LogP ]:
1.53170

[ Vapour Pressure ]:
778mmHg at 25°C

[ Index of Refraction ]:
1.389

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AK2950000

CHEMICAL NAME :: Acetimidic acid, methyl ester, hydrochloride

CAS REGISTRY NUMBER :: 14777-27-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H7-N-O.Cl-H

MOLECULAR WEIGHT :: 109.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 3 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 180,121,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AK2950000

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Arginyl residues and thermal stability in proteins.

Mol. Cell Biochem. 71(2) , 121-7, (1986)

Guanidination and amidination of bovine serum albumin, yeast enolase and yeast alcohol dehydrogenase were accompanied by increases in thermal stability at lower extents of modification. Decreases in t...

Comparative evaluation of fifteen anti-sickling agents.

Blood 61(4) , 693-704, (1983)

Fifteen compounds reported to be inhibitors of gelation or sickling were studied by standard methods. These tests included (1) the determination of the solubility of deoxyhemoglobin S or Csat, (2) eva...

Identification of "buried" lysine residues in two variants of chloramphenicol acetyltransferase specified by R-factors.

Biochem. J. 193(2) , 525-39, (1981)

Two variants of chloramphenicol acetyltransferase which are specified by genes on plasmids found in Gram-negative bacteria were subjected to amidination with methyl acetimidate to determine the relati...