thunberginol c

Names

[ Name ]:
thunberginol c

[Synonym ]:
6,8-Dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-1H-isochromen-1-one
1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-(4-hydroxyphenyl)-
thunberginol c

Biological Activity

[Description]:

Thunberginol C is a natural product that can be isolated from Hydrangea macrophyll. Thunberginol C attenuates stress-induced anxiety. Thunberginol C also has antimicrobial and antiallergic activity[1][2].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Lee J, et al. Hydrangea macrophylla and Thunberginol C Attenuate Stress-Induced Anxiety in Mice. Antioxidants (Basel). 2022 Jan 26;11(2):234.

[2]. Yoshikawa M, et al. Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium. Chem Pharm Bull (Tokyo). 1992 Dec;40(12):3352-4.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
595.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₂O₅

[ Molecular Weight ]:
272.253

[ Flash Point ]:
232.0±23.6 °C

[ Exact Mass ]:
272.068481

[ PSA ]:
86.99000

[ LogP ]:
2.22

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.693

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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