PF-06885249
Names
[ CAS No. ]:
1467059-70-6
[ Name ]:
PF-06885249
Biological Activity
[Description]:
PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes.
[References]
References 1. Cokorinos EC, et al. Cell Metab. 2017 May 2;25(5):1147-1159. View Related Products by Target AMPK
Chemical & Physical Properties
[ Molecular Formula ]:
C17H16ClN3O3
[ Molecular Weight ]:
345.783