PF-06885249

Names

[ Name ]:
PF-06885249

Biological Activity

[Description]:

PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes.

[References]

References 1. Cokorinos EC, et al. Cell Metab. 2017 May 2;25(5):1147-1159. View Related Products by Target AMPK

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆ClN₃O₃

[ Molecular Weight ]:
345.783

Related Compounds

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