1467059-70-6
1467059-70-6 structure
- Name: PF-06885249
- Chemical Name: PF-249
- CAS Number: 1467059-70-6
- Molecular Formula: C17H16ClN3O3
- Molecular Weight: 345.783
- Catalog: Signaling Pathways Epigenetics AMPK
- Create Date: 2020-01-11 17:45:02
- Modify Date: 2024-01-11 17:33:16
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PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes.
| Name | PF-249 |
|---|
| Description | PF-249 is a potent, selective AMPK β1-containing complexes activator; increases the phosphorylation of the AMPK substrate ACC at S79 with EC50 of 296 nM, potently inhibits de novo lipogenesis (IC50=15 nM) in primary rat hepatocytes. |
|---|---|
| References | References 1. Cokorinos EC, et al. Cell Metab. 2017 May 2;25(5):1147-1159. View Related Products by Target AMPK |
| Molecular Formula | C17H16ClN3O3 |
|---|---|
| Molecular Weight | 345.783 |