Chlorajapolide F

Names

[ CAS No. ]:
1461760-59-7

[ Name ]:
Chlorajapolide F

[Synonym ]:
Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 4a,5,5a,6,6a,6b,7,7a-octahydro-7-hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-, (4aS,5aS,6aR,6bS,7S,7aR)-
(4aS,5aS,6aR,6bS,7S,7aR)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one

Biological Activity

[Description]:

Chlorajapolide F is a nature product that could be isolated from the aerial part of Chloranthus japonicas. Chlorajapolide F has low cytotoxic activity against NCI-H460 and SMMC-7721 cell lines[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Chlorajapolide F (compound 1) 对 NCI-H460 和 SMMC-7721 细胞系具有细胞毒活性，IC50 值 >50 μg/L。

[References]

[1]. Zhang M, et, al. Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities. Fitoterapia. 2012 Dec;83(8):1604-9.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
454.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H20O4

[ Molecular Weight ]:
276.328

[ Flash Point ]:
169.9±22.2 °C

[ Exact Mass ]:
276.136169

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.583

Related Compounds

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