8-epi-Chlorajapolide F

Names

[ CAS No. ]:
863301-69-3

[ Name ]:
8-epi-Chlorajapolide F

[Synonym ]:
Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 4a,5,5a,6,6a,6b,7,7a-octahydro-7-hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-, (4aS,5aS,6aR,6bS,7S,7aS)-
(4aS,5aS,6aR,6bS,7S,7aS)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one

Biological Activity

[Description]:

8-epi-Chlorajapolide F (compound 1) a sesquiterpene that can be isolated from the aboveground part of the Chloranthus japonicus. 8-epi-Chlorajapolide has few cytotoxic to human cancer cell lines NCI-H460 and SMMC-7721 (IC50s>50 μg/mL)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Zhang M, et al. Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities. Fitoterapia. 2012 Dec;83(8):1604-9.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
454.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H20O4

[ Molecular Weight ]:
276.328

[ Flash Point ]:
169.9±22.2 °C

[ Exact Mass ]:
276.136169

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.583

Related Compounds

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