1461760-59-7

1461760-59-7 structure

Name: Chlorajapolide F
Chemical Name: (4aS,5aS,6aR,6bS,7S,7aR)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
CAS Number: 1461760-59-7
Molecular Formula: C₁₆H₂₀O₄
Molecular Weight: 276.328
Catalog: Research Areas Cancer
Create Date: 2018-07-03 17:03:29
Modify Date: 2025-08-22 15:40:49
Chlorajapolide F is a nature product that could be isolated from the aerial part of Chloranthus japonicas. Chlorajapolide F has low cytotoxic activity against NCI-H460 and SMMC-7721 cell lines[1].

Name	(4aS,5aS,6aR,6bS,7S,7aR)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one
Synonyms	Cycloprop[2,3]indeno[5,6-b]furan-2(4H)-one, 4a,5,5a,6,6a,6b,7,7a-octahydro-7-hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-, (4aS,5aS,6aR,6bS,7S,7aR)- (4aS,5aS,6aR,6bS,7S,7aR)-7-Hydroxy-7a-methoxy-3,6b-dimethyl-5-methylene-4a,5,5a,6,6a,6b,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(4H)-one

Description	Chlorajapolide F is a nature product that could be isolated from the aerial part of Chloranthus japonicas. Chlorajapolide F has low cytotoxic activity against NCI-H460 and SMMC-7721 cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Chlorajapolide F (compound 1) 对 NCI-H460 和 SMMC-7721 细胞系具有细胞毒活性，IC50 值 >50 μg/L。
References	[1]. Zhang M, et, al. Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities. Fitoterapia. 2012 Dec;83(8):1604-9.