5'-Chloro-2'-hydroxyacetophenone

Names

[ Name ]:
5'-Chloro-2'-hydroxyacetophenone

[Synonym ]:
5-Chloro-2-hydroxyacetophenone
5'-chloro-2'- hydroxyacetophenone
Ethanone, 1- (5-chloro-2-hydroxyphenyl)-
5'-Chloro-2'-hydroxyacetophenone
EINECS 215-916-8
2-acetyl-4-chlorophenol
Acetophenone,5'-chloro-2'-hydroxy
2'-Hydroxy-5'-chloroacetophenone
1-(5-Chloro-2-hydroxyphenyl)ethanone
5′-Chloro-2′-hydroxyacetophenone
Acetophenone, 5'-chloro-2'-hydroxy-
Ethanone, 1-(5-chloro-2-hydroxyphenyl)-
MFCD00067788

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
270.9±25.0 °C at 760 mmHg

[ Melting Point ]:
54-56 °C(lit.)

[ Molecular Formula ]:
C₈H₇ClO₂

[ Molecular Weight ]:
170.593

[ Flash Point ]:
117.6±23.2 °C

[ Exact Mass ]:
170.013458

[ PSA ]:
37.30000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.569

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and evaluation of antirhinovirus activity of 3-hydroxy and 3-methoxy 2-styrylchromones.

Antivir. Chem. Chemother. 14(4) , 195-203, (2003)

Recently, we identified 2-styrylchromones as a new class of antirhinovirus flavonoids with moderate activity against both rhinovirus groups A and B. In order to improve the antiviral effect of the fir...

A Highly Efficient and Practical Synthesis of Chromene Derivatives Using Ring-Closing Olefin Metathesis.

J. Org. Chem. 63(3) , 864-66, (1998)

Catabolism of 2,7-dichloro- and 2,4,8-trichlorodibenzofuran by Sphingomonas sp strain RW1.

J. Ind. Microbiol. Biotechnol. 23(4-5) , 359-63, (1999)

Due to their physicochemical and toxicological properties, polychlorinated dibenzofurans are regarded as a class of compounds providing reason for serious environmental concern. While the nonhalogenat...