YM 26734

Names

[ Name ]:
YM 26734

[Synonym ]:
YM26734

Biological Activity

[Description]:

YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase

Research Areas >> Inflammation/Immunology

[Target]

sPLA2

[References]

[1]. Miyake A, et al. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110(1):447-53.

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
797.832ºC at 760 mmHg

[ Molecular Formula ]:
C₄₅H₆₂O₈

[ Molecular Weight ]:
730.96900

[ Flash Point ]:
228.539ºC

[ Exact Mass ]:
730.44400

[ PSA ]:
144.52000

[ LogP ]:
12.07750

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.572

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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