YM 511

Names

[ Name ]:
YM 511

[Synonym ]:
ym-511

Biological Activity

[Description]:

YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Others >> Aromatase

[References]

[1]. M Kudoh, et al. The potent and selective inhibition of estrogen production by non-steroidal aromatase inhibitor, YM511. J Steroid Biochem Mol Biol. 1995 Sep;54(5-6):265-71.

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Boiling Point ]:
551.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₂BrN₅

[ Molecular Weight ]:
354.20400

[ Flash Point ]:
287.6ºC

[ Exact Mass ]:
353.02800

[ PSA ]:
57.74000

[ LogP ]:
3.38218

[ Vapour Pressure ]:
3.18E-12mmHg at 25°C

[ Index of Refraction ]:
1.675

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.