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Atrovastatin-PEG3-FITC

Names

[ CAS No. ]:
1440755-31-6

[ Name ]:
Atrovastatin-PEG3-FITC

Biological Activity

[Description]:

Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS-PDEδ


[References]

[1]. Gunther Zimmermann, et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signaling. Nature. 2013 May 30;497(7451):638-42.

[2]. Yan Jiang, et al. Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors. J Med Chem. 2017 Nov 22;60(22):9400-9406.

Chemical & Physical Properties

[ Molecular Formula ]:
C64H68FN5O12S

[ Molecular Weight ]:
1150.31

Related Compounds