Iodoacetamide
Names
[ CAS No. ]:
144-48-9
[ Name ]:
Iodoacetamide
[Synonym ]:
MFCD00008028
carbamoylmethyl iodide
2-Iodo-acetamide
USAF D-1
Monoiodoacetamide
2-iodoacetamido
Acetamide, 2-iodo-
Iodoacetamide
ACETAMIDE,2-IODO
2-Iodoacetamide
Surauto
EINECS 205-630-1
Biological Activity
[Description]:
[Related Catalog]:
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
2.3±0.1 g/cm3
[ Boiling Point ]:
297.1±23.0 °C at 760 mmHg
[ Melting Point ]:
92-95 °C(lit.)
[ Molecular Formula ]:
C2H4INO
[ Molecular Weight ]:
184.964
[ Flash Point ]:
133.5±22.6 °C
[ Exact Mass ]:
184.933746
[ PSA ]:
43.09000
[ LogP ]:
-0.19
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.602
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable, but light sensitive. Incompatible with strong oxidizing agents, strong bases, reducing agents, acids.
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC4200000
- CHEMICAL NAME :
- Acetamide, 2-iodo-
- CAS REGISTRY NUMBER :
- 144-48-9
- BEILSTEIN REFERENCE NO. :
- 1739080
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C2-H4-I-N-O
- MOLECULAR WEIGHT :
- 184.97
- WISWESSER LINE NOTATION :
- ZV1I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 74 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1480 mg/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- STBIBN Studia Biophysica. (Akademie-Verlag GmbH, Postfach 1233, Berlin DDR-1086, Ger. Dem. Rep.) V.1- 1966- Volume(issue)/page/year: 50,97,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4435 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H317-H334-H413
[ Precautionary Statements ]:
P261-P280-P301 + P310-P342 + P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R25;R36/37/38;R43
[ Safety Phrases ]:
S22-S36/37-S45-S37/39-S26-S24
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
AC4200000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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