stilbene oxide

Names

[ Name ]:
stilbene oxide

[Synonym ]:
2,3-Diphenyloxirane
Bibenzyl, α,α'-epoxy- (8CI)
stilbene oxide
MFCD00064311
EINECS 215-877-7
TRANS-STILBENE OXIDE
2,3-Diphenyl-oxirane
Oxirane, 2,3-diphenyl-
Bibenzyl, α,α'-epoxy-
trans-2,3-Diphenylethylene Oxide

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
304.5±11.0 °C at 760 mmHg

[ Melting Point ]:
65-67 °C(lit.)

[ Molecular Formula ]:
C₁₄H₁₂O

[ Molecular Weight ]:
196.245

[ Flash Point ]:
133.4±15.5 °C

[ Exact Mass ]:
196.088821

[ PSA ]:
12.53000

[ LogP ]:
3.39

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.608

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT4391500

CHEMICAL NAME :: Bibenzyl, alpha,alpha'-epoxy-, trans-

CAS REGISTRY NUMBER :: 1439-07-2

LAST UPDATED :: 199406

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H12-O

MOLECULAR WEIGHT :: 196.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 40 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 290,165,1993

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DT4391500

[ HS Code ]:
2910900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.

Drug Metab. Dispos. 31(9) , 1176-86, (2003)

Treatment with the microsomal enzyme inducer trans-stilbene oxide (TSO) can decrease biliary excretion of acetaminophen-glucuronide (AA-GLUC) and increase efflux of AA-GLUC into blood. The hepatic can...

The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.

Drug Metab. Pharmacokinet. 30(1) , 75-81, (2015)

Lysophosphatidic acids (LPAs) are phospholipids which have many physiological and pathophysiological functions. The human soluble epoxide hydrolase (sEH) plays a role in the metabolism of xenobiotics ...

A test to determine the nature and presence of the memory effect columns packed with the amylose tris(3,5-dimethylphenylcarbamate) stationary phase.

J. Chromatogr. A. 1218(37) , 6302-7, (2011)

Acid/base mobile phase modifiers affect enantioseparations in ways that are not fully understood yet, for the lack of systematic studies. This makes chiral analysis of some pharmaceuticals difficult t...