Ethynyl 4-methylphenyl sulfone

Names

[ Name ]:
Ethynyl 4-methylphenyl sulfone

[Synonym ]:
Tosylacetylene
Benzene, 1-(ethynylsulfonyl)-4-methyl-
p-Toluenesulfonylacetylene
Ethynyl 4-methylphenyl sulfone
1-ethynylsulfonyl-4-methylbenzene
MFCD00191647
p-Toluenesulfonylacetylene Tosylacetylene
1-(Ethynylsulfonyl)-4-methylbenzene

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
297.9±33.0 °C at 760 mmHg

[ Melting Point ]:
73-74ºC(lit.)

[ Molecular Formula ]:
C₉H₈O₂S

[ Molecular Weight ]:
180.224

[ Flash Point ]:
155.6±18.1 °C

[ Exact Mass ]:
180.024506

[ PSA ]:
42.52000

[ LogP ]:
2.43

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.553

[ Water Solubility ]:
organic solvents: soluble(lit.)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2904100000

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2904100000

[ Summary ]:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Tosvinyl and besvinyl as protecting groups of imides, azinones, nucleosides, sultams, and lactams. Catalytic conjugate additions to tosylacetylene.

J. Org. Chem. 79(18) , 8826-34, (2014)

The use of the 2-(4-methylphenylsulfonyl)ethenyl (tosvinyl, Tsv) group for the protection of the NH group of a series of imides, azinones (including AZT), inosines, and cyclic sulfonamides has been ex...

Efficient and practical method for synthesizing optically active indan-2-ols by the Ti(O-i-Pr)(4)/2 i-PrMgCl-mediated metalative Reppe reaction.

J. Org. Chem. 68(12) , 4980-3, (2003)

An efficient and practical synthesis of optically active indan-2-ols 1 has been developed starting from readily accessible optically active 4-siloxy-1,6-alkadiynes 2 and ethynyl p-tolyl sulfone, where...

A Simplified Method for the Preparation of Ethynyl P-Tolyl Sulfone and Ethynyl Phenyl Sulfone. Chen Z and Trudell ML.

Synth. Commun. 24(21) , 3149-55, (1994)