CK1-IN-2

Names

[ Name ]:
CK1-IN-2

Biological Activity

[Description]:

CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase

Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[Target]

CKIα:123 nM (IC50)

[References]

[1]. Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₂FN₃O₂

[ Molecular Weight ]:
309.29

Related Compounds

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