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1383376-92-8

1383376-92-8 structure

1383376-92-8 structure

Name: CK1-IN-2
Chemical Name: CK1-IN-2
CAS Number: 1383376-92-8
Molecular Formula: C₁₇H₁₂FN₃O₂
Molecular Weight: 309.29
Catalog: Signaling Pathways Cell Cycle/DNA Damage Casein Kinase
Create Date: 2023-11-07 18:06:38
Modify Date: 2025-11-05 18:21:33
CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].

Name	CK1-IN-2

Description	CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor with an IC50 values of 123, 19.8, 26.8, 74.3 nM for CK1a, CK1d, CK1e, p38a, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase
Target	CKIα:123 nM (IC50)
References	[1]. Joris De Maeyer, et al. Casein kinase 1 inhibitors for use in the treatment of diseases related to dux4 expression such as muscular dystrophy and cancer. WO2020249717A1.

Molecular Formula	C₁₇H₁₂FN₃O₂
Molecular Weight	309.29

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