(±)-Marmesin

Names

[ Name ]:
(±)-Marmesin

[Synonym ]:
2-(2-Hydroxy-2-propanyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
marmesin
2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-
2-(1-Hydroxy-1-methyl-ethyl)-2,3-dihydro-furo[3,2-g]chromen-7-one
2-(1-Hydroxy-1-methylethyl)-2,3-dihydrofuro[3,2-g]chromen-7-one

Biological Activity

[Description]:

(±)-Marmesin is a good precursor of the linear furanocoumarins. (±)-Marmesin derivatives have high degree of acetylcholinesterase inhibitory property[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE

[References]

[1]. Austin D J, et al. Furanocoumarin biosynthesis in Ruta graveolens cell cultures[J]. Phytochemistry, 1973, 12(7): 1657-1667.

[2]. Rao J M, et al. Pharmaceutical composition useful as acetylcholinesterase inhibitors: U.S. Patent 8,188,143[P]. 2012-5-29.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
434.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₄O₄

[ Molecular Weight ]:
246.259

[ Flash Point ]:
168.0±22.2 °C

[ Exact Mass ]:
246.089203

[ LogP ]:
1.69

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds

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