LY 233536

Names

[ CAS No. ]:
136845-59-5

[ Name ]:
LY 233536

[Synonym ]:
(3R,4aS,6R,8aS)-6-(2H-Tetrazol-5-ylmethyl)decahydro-3-isoquinolinecarboxylic acid
3-Isoquinolinecarboxylic acid, decahydro-6-(2H-tetrazol-5-ylmethyl)-, (3R,4aS,6R,8aS)-
LY233536

Biological Activity

[Description]:

LY 233536 is a competitive NMDA receptor antagonist[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. Yoshiyama M, et al. Effects of LY274614, a competitive NMDA receptor antagonist, on the micturition reflex in the urethane-anaesthetized rat. Br J Pharmacol. 1993;110(1):77-86.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
522.8±56.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H19N5O2

[ Molecular Weight ]:
265.31

[ Flash Point ]:
270.0±31.8 °C

[ Exact Mass ]:
265.153870

[ LogP ]:
-0.43

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.573

Related Compounds