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DPP-IV-IN-2

Names

[ CAS No. ]:
136259-18-2

[ Name ]:
DPP-IV-IN-2

[Synonym ]:
lys(4-nitro-Z)pyrrolidide
Lys-Z-nitro-pyrrolidine
Lys[Z(NO2)] pyrrolidide
DPP-IV-IN-2

Biological Activity

[Description]:

DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase
Research Areas >> Inflammation/Immunology
Research Areas >> Neurological Disease

[Target]

IC50: 0.1 μM (DPIV), 0.95 μM (DP8/9)[1]


[References]

[1]. Ansorge S, et al. Novel aspects of cellular action of dipeptidyl peptidase IV/CD26. Biol Chem. 2011 Mar;392(3):153-68.


[Related Small Molecules]

Talabostat mesylate | Linagliptin | Teneligliptin | Vildagliptin (LAF-237) | AZD7986 | Omarigliptin | Anagliptin | Trelagliptin | Gemigliptin | DBPR108 | Diprotin A TFA (Ile-Pro-Pro (TFA)) | Saikogenin A | UAMC 00039 dihydrochloride | Dutogliptin | Gosogliptin

Chemical & Physical Properties

[ Molecular Formula ]:
C18H26N4O5

[ Molecular Weight ]:
378.42300

[ Exact Mass ]:
378.19000

[ PSA ]:
130.48000

[ LogP ]:
3.49330

Related Compounds

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