1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine

Names

[ CAS No. ]:
136020-18-3

[ Name ]:
1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine

[Synonym ]:
2',3'-Dideoxy-hexopyranosyl cytidine

Biological Activity

[Description]:

1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.63g/cm3

[ Boiling Point ]:
491.8ºC at 760mmHg

[ Molecular Formula ]:
C10H15N3O5

[ Molecular Weight ]:
257.24

[ Flash Point ]:
251.3ºC

[ Exact Mass ]:
241.10600

[ PSA ]:
111.59000

[ Vapour Pressure ]:
9.77E-12mmHg at 25°C

[ Index of Refraction ]:
1.691

Synthetic Route

Click to get detail synthetic route

Related Compounds

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